Research studies

Below are several of 1000+ studies of the therapeutic benefits of hydrogen gas. Note that this does not mean that hydrogen gas can cure, heal or treat any of the following issues; however, based on emerging studies, the results are hopeful and more studies are still in progress with exciting findings. Click each finding to view various independent studies on the various topics.

Molecular hydrogen studies in general:

Therapeutic medical gas

Diverse animal and human disease models

Improving quality of life after radiotherapy treatment

Alleviating free radical damage

Medical application of hydrogen gas in hematological issues

Improvements of moods, anxiety and autonomic nerve function


Growth suppression in cancer treatments (and alleviate side effects caused by chemotherapy)

Lung cancer (represses progression in lung cancer)

Colorectal cancer (improve prognosis via invigorating exhausted T cells)


Enhancement of alveolar in lungs (in mice)

Lung function improvement (in mice)


Acid Reflux/Heartburn

Gastric injury

Gastric mucosal injury

Inflammatory Bowel Disease (IBD) (in mice)

T cells:

Improve cancer patients outcomes in general via T cells

Hydrogen gas leads to better (nivolumab) outcomes with lung cancer patients, restores exhausted T cells


Inflammation from exercise

Muscle fatigue

Muscle performance and delay of muscle soreness

Other issues:

Allergies (allergic rhinitis, in mice)


Brain injury (in mice)

Cardiovascular disorders

Chlorpyrifos-induced neurotoxicity (in rats; pesticides that affect the brain)

Chlorpyrifos-induced hepatotoxicity (in rats; pesticides that affect the liver)

Depression, anxiety, and traumatic brain injury

Diabetes Type I (in mice)

Diabetes Type II

Diabetes Type II (also obesity)

Endometriosis (in rats)

Fatty liver disease (in mice)

Infertility, female (in mice)

Infertility, male

Infertility, male (abstract)

Kidney injury (in rats)

Lung injury (in rats)

Multiple Sclerosis (in mice)

Myocardial ischemia-reperfusion injury (via Nrf2 pathway activation; in rats)

Neurodegeneration (in mice)

Neurological/metabolic/inflammatory diseases

Obesity & metabolism (in mice)


Radiation-induced heart damage (in rats)

Rheumatoid Arthritis

Rheumatoid Arthritis (in mice)

Indirect studies:

Autism (while there have been no direct studies linked to autism and H2 so far, some probable causes of autism may include altered ghrelin levels and damage to the blood brain barrier. H2 has shown to repair the blood-brain barrier and increase neuroprotective ghrelin secretion in mice)

Lupus (while no direct studies have been linked to lupus and H2 as yet, studies have indicated that T-cell regulation may reverse lupus. Numerous studies have shown that H2 positively affects T cells directly)

Click here to learn more about how the body reacts with hydrogen gas
Learn about free radicals and antioxidants here